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miR-23a Regulates Cardiomyocyte Apoptosis by Targeting Manganese Superoxide Dismutase

Cardiomyocyte apoptosis is initiated by various cellular insults and accumulated cardiomyocyte apoptosis leads to the pathogenesis of heart failure. Excessive reactive oxygen species (ROS) provoke apoptotic cascades. Manganese superoxide dismutase (MnSOD) is an important antioxidant enzyme that conv...

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Detalles Bibliográficos
Autores principales: Long, Bo, Gan, Tian-Yi, Zhang, Rong-Cheng, Zhang, Yu-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582300/
https://www.ncbi.nlm.nih.gov/pubmed/28756653
http://dx.doi.org/10.14348/molcells.2017.0012