Signatures derived from increase in SHARPIN gene copy number are associated with poor prognosis in patients with breast cancer

We report three signatures produced from SHARPIN gene copy number increase (GCN-Increase) and their effects on patients with breast cancer (BC). In the Metabric dataset (n = 2059, cBioPortal), SHARPIN GCN-Increase occurs preferentially or mutual exclusively with mutations in TP53, PIK3CA, and CDH1....

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Detalles Bibliográficos
Autores principales: Ojo, Diane, Seliman, Maryam, Tang, Damu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582379/
https://www.ncbi.nlm.nih.gov/pubmed/28879097
http://dx.doi.org/10.1016/j.bbacli.2017.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582379/
https://www.ncbi.nlm.nih.gov/pubmed/28879097
http://dx.doi.org/10.1016/j.bbacli.2017.07.004

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