BayFish: Bayesian inference of transcription dynamics from population snapshots of single-molecule RNA FISH in single cells

Single-molecule RNA fluorescence in situ hybridization (smFISH) provides unparalleled resolution in the measurement of the abundance and localization of nascent and mature RNA transcripts in fixed, single cells. We developed a computational pipeline (BayFish) to infer the kinetic parameters of gene...

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Detalles Bibliográficos
Autores principales: Gómez-Schiavon, Mariana, Chen, Liang-Fu, West, Anne E., Buchler, Nicolas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582403/
https://www.ncbi.nlm.nih.gov/pubmed/28870226
http://dx.doi.org/10.1186/s13059-017-1297-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582403/
https://www.ncbi.nlm.nih.gov/pubmed/28870226
http://dx.doi.org/10.1186/s13059-017-1297-9

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