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BayFish: Bayesian inference of transcription dynamics from population snapshots of single-molecule RNA FISH in single cells
Single-molecule RNA fluorescence in situ hybridization (smFISH) provides unparalleled resolution in the measurement of the abundance and localization of nascent and mature RNA transcripts in fixed, single cells. We developed a computational pipeline (BayFish) to infer the kinetic parameters of gene...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582403/ https://www.ncbi.nlm.nih.gov/pubmed/28870226 http://dx.doi.org/10.1186/s13059-017-1297-9 |