PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes

Osteoarthritis (OA) is a degenerative joint disease affecting a large population of people. Although the elevated expression of PKR (double stranded RNA-dependent protein kinase) and MMP-13 (collagenase-3) have been indicated to play pivotal roles in the pathogenesis of OA, the exact mechanism under...

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Detalles Bibliográficos
Autores principales: Ma, Ching-Hou, Wu, Chin-Hsien, Jou, I.-Ming, Tu, Yuan-Kun, Hung, Ching-Hsia, Hsieh, Pei-Ling, Tsai, Kun-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582648/
https://www.ncbi.nlm.nih.gov/pubmed/28869834
http://dx.doi.org/10.1016/j.redox.2017.08.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582648/
https://www.ncbi.nlm.nih.gov/pubmed/28869834
http://dx.doi.org/10.1016/j.redox.2017.08.011

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