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Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways

Despite the increasingly important role of Hippo-Yap in hepatocellular carcinoma (HCC) development and progression, little insight is available at the time regarding the specifics interaction of Yap and cancer cells migration. Here, we identified the mechanism by which tumor-intrinsic Yap deletion r...

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Detalles Bibliográficos
Autores principales: Shi, Chen, Cai, Yong, Li, Yongheng, Li, Ye, Hu, Nan, Ma, Sai, Hu, Shunying, Zhu, Pingjun, Wang, Weihu, Zhou, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582718/
https://www.ncbi.nlm.nih.gov/pubmed/28869833
http://dx.doi.org/10.1016/j.redox.2017.08.013