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Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade

S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6, which modifies key proteins of the endoplasmic reticulum, is controlled by an upstream palmitoyltransferase, ZDHHC16,...

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Detalles Bibliográficos
Autores principales: Abrami, Laurence, Dallavilla, Tiziano, Sandoz, Patrick A, Demir, Mustafa, Kunz, Béatrice, Savoglidis, Georgios, Hatzimanikatis, Vassily, van der Goot, F Gisou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582869/
https://www.ncbi.nlm.nih.gov/pubmed/28826475
http://dx.doi.org/10.7554/eLife.27826