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Identification and dynamics of the human ZDHHC16-ZDHHC6 palmitoylation cascade
S-Palmitoylation is the only reversible post-translational lipid modification. Knowledge about the DHHC palmitoyltransferase family is still limited. Here we show that human ZDHHC6, which modifies key proteins of the endoplasmic reticulum, is controlled by an upstream palmitoyltransferase, ZDHHC16,...
Autores principales: | Abrami, Laurence, Dallavilla, Tiziano, Sandoz, Patrick A, Demir, Mustafa, Kunz, Béatrice, Savoglidis, Georgios, Hatzimanikatis, Vassily, van der Goot, F Gisou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582869/ https://www.ncbi.nlm.nih.gov/pubmed/28826475 http://dx.doi.org/10.7554/eLife.27826 |
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