IL-17A Enhances Microglial Response to OGD by Regulating p53 and PI3K/Akt Pathways with Involvement of ROS/HMGB1

Cerebral ischemia-reperfusion injury (IRI) has a complex pathogenesis, and interleukin-17 (IL-17) is a newly identified class of the cytokine family that plays an important role in ischemic inflammation. An oxygen-glucose deprivation (OGD) model showed that IL-17A expression was significantly up-reg...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Yang, Ning, Mo, Zhi-Ming, Lin, Shao-Peng, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583146/
https://www.ncbi.nlm.nih.gov/pubmed/28912678
http://dx.doi.org/10.3389/fnmol.2017.00271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583146/
https://www.ncbi.nlm.nih.gov/pubmed/28912678
http://dx.doi.org/10.3389/fnmol.2017.00271

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