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IL-17A Enhances Microglial Response to OGD by Regulating p53 and PI3K/Akt Pathways with Involvement of ROS/HMGB1
Cerebral ischemia-reperfusion injury (IRI) has a complex pathogenesis, and interleukin-17 (IL-17) is a newly identified class of the cytokine family that plays an important role in ischemic inflammation. An oxygen-glucose deprivation (OGD) model showed that IL-17A expression was significantly up-reg...
Autores principales: | Zhang, Bin, Yang, Ning, Mo, Zhi-Ming, Lin, Shao-Peng, Zhang, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583146/ https://www.ncbi.nlm.nih.gov/pubmed/28912678 http://dx.doi.org/10.3389/fnmol.2017.00271 |
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