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Increased Hippocampal ProBDNF Contributes to Memory Impairments in Aged Mice
Memory decline during aging or accompanying neurodegenerative diseases, represents a major health problem. Neurotrophins have long been considered relevant to the mechanisms of aging-associated cognitive decline and neurodegeneration. Mature Brain-Derived Neurotrophic Factor (BDNF) and its precursor...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583170/ https://www.ncbi.nlm.nih.gov/pubmed/28912711 http://dx.doi.org/10.3389/fnagi.2017.00284 |