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Increased Hippocampal ProBDNF Contributes to Memory Impairments in Aged Mice

Memory decline during aging or accompanying neurodegenerative diseases, represents a major health problem. Neurotrophins have long been considered relevant to the mechanisms of aging-associated cognitive decline and neurodegeneration. Mature Brain-Derived Neurotrophic Factor (BDNF) and its precursor...

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Detalles Bibliográficos
Autores principales: Buhusi, Mona, Etheredge, Chris, Granholm, Ann-Charlotte, Buhusi, Catalin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583170/
https://www.ncbi.nlm.nih.gov/pubmed/28912711
http://dx.doi.org/10.3389/fnagi.2017.00284