MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1

Murine double minute 2 (MDM2) is an E3-ubiquitin ligase critical for various biological functions. Previous data have revealed an indispensable role of MDM2 in kidney homeostasis. However, its role in glomerular mesangial cell (GMC) proliferation and extracellular matrix (ECM) accumulation during hy...

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Detalles Bibliográficos
Autores principales: Lei, Chun-Tao, Tang, Hui, Ye, Chen, You, Chao-Qun, Zhang, Jiao, Zhang, Chun-Yun, Xiong, Wei, Su, Hua, Zhang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583188/
https://www.ncbi.nlm.nih.gov/pubmed/28871126
http://dx.doi.org/10.1038/s41598-017-10927-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583188/
https://www.ncbi.nlm.nih.gov/pubmed/28871126
http://dx.doi.org/10.1038/s41598-017-10927-5

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