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Small molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways

Osteoporosis results from the imbalance between bone resorption and bone formation, and restoring the normal balance of bone remodeling is highly desirable for identification of better treatment. In this study, using a cell-based high-throughput screening model representing Runt-related transcriptio...

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Detalles Bibliográficos
Autores principales: Zhao, Xiao-li, Chen, Jin-jing, Zhang, Guo-ning, Wang, Yu-cheng, Si, Shu-yi, Chen, Lin-Feng, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583318/
https://www.ncbi.nlm.nih.gov/pubmed/28871136
http://dx.doi.org/10.1038/s41598-017-10929-3