A novel mathematical model of protein-bound uremic toxin kinetics during hemodialysis

Protein-bound uremic toxins (PBUTs) are difficult to remove by conventional hemodialysis; a high degree of protein binding reduces the free fraction of toxins and decreases their diffusion across dialyzer membranes. Mechanistic understanding of PBUT kinetics can open new avenues to improve their dia...

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Detalles Bibliográficos
Autores principales: Maheshwari, Vaibhav, Thijssen, Stephan, Tao, Xia, Fuertinger, Doris, Kappel, Franz, Kotanko, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583320/
https://www.ncbi.nlm.nih.gov/pubmed/28871178
http://dx.doi.org/10.1038/s41598-017-10981-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583320/
https://www.ncbi.nlm.nih.gov/pubmed/28871178
http://dx.doi.org/10.1038/s41598-017-10981-z

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