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Analysis of population-specific pharmacogenomic variants using next-generation sequencing data
Functional rare variants in drug-related genes are believed to be highly differentiated between ethnic- or racial populations. However, knowledge of population differentiation (PD) of rare single-nucleotide variants (SNVs), remains widely lacking, with the highest fixation indices, (F(st) values), f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583360/ https://www.ncbi.nlm.nih.gov/pubmed/28871186 http://dx.doi.org/10.1038/s41598-017-08468-y |