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Engineering a riboswitch-based genetic platform for the self-directed evolution of acid-tolerant phenotypes

Environmental pH is a fundamental signal continuously directing the metabolism and behavior of living cells. Programming the precise cellular response toward environmental pH is, therefore, crucial for engineering cells for increasingly sophisticated functions. Herein, we engineer a set of riboswitc...

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Detalles Bibliográficos
Autores principales: Pham, Hoang Long, Wong, Adison, Chua, Niying, Teo, Wei Suong, Yew, Wen Shan, Chang, Matthew Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583362/
https://www.ncbi.nlm.nih.gov/pubmed/28871084
http://dx.doi.org/10.1038/s41467-017-00511-w