Development of a luciferase-based biosensor to assess enterovirus 71 3C protease activity in living cells

Enterovirus 71 (EV71) is a major pathogen of hand, foot, and mouth disease (HFMD). To date, no antiviral drug has been approved to treat EV71 infection. Due to the essential role that EV71 3 C protease (3C(pro)) plays in the viral life cycle, it is generally considered as a highly appealing target f...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Ke, Xianliang, Zheng, Caishang, Liu, Yan, Xie, Li, Zheng, Zhenhua, Wang, Hanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583365/
https://www.ncbi.nlm.nih.gov/pubmed/28871120
http://dx.doi.org/10.1038/s41598-017-10840-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583365/
https://www.ncbi.nlm.nih.gov/pubmed/28871120
http://dx.doi.org/10.1038/s41598-017-10840-x

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