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Lipidomic dysregulation within the lung parenchyma following whole-thorax lung irradiation: Markers of injury, inflammation and fibrosis detected by MALDI-MSI

Radiation-induced lung injury (RILI) is a delayed effect of acute radiation exposure that can limit curative cancer treatment therapies and cause lethality following high-dose whole-thorax lung irradiation (WTLI). To date, the exact mechanisms of injury development following insult remain ill-define...

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Detalles Bibliográficos
Autores principales: Carter, Claire L., Jones, Jace W., Farese, Ann M., MacVittie, Thomas J., Kane, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583385/
https://www.ncbi.nlm.nih.gov/pubmed/28871103
http://dx.doi.org/10.1038/s41598-017-10396-w