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Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells

Assessing the impact of genomic alterations on protein networks is fundamental in identifying the mechanisms that shape cancer heterogeneity. We have used isobaric labeling to characterize the proteomic landscapes of 50 colorectal cancer cell lines and to decipher the functional consequences of soma...

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Detalles Bibliográficos
Autores principales: Roumeliotis, Theodoros I., Williams, Steven P., Gonçalves, Emanuel, Alsinet, Clara, Del Castillo Velasco-Herrera, Martin, Aben, Nanne, Ghavidel, Fatemeh Zamanzad, Michaut, Magali, Schubert, Michael, Price, Stacey, Wright, James C., Yu, Lu, Yang, Mi, Dienstmann, Rodrigo, Guinney, Justin, Beltrao, Pedro, Brazma, Alvis, Pardo, Mercedes, Stegle, Oliver, Adams, David J., Wessels, Lodewyk, Saez-Rodriguez, Julio, McDermott, Ultan, Choudhary, Jyoti S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583477/
https://www.ncbi.nlm.nih.gov/pubmed/28854368
http://dx.doi.org/10.1016/j.celrep.2017.08.010