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Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells
Assessing the impact of genomic alterations on protein networks is fundamental in identifying the mechanisms that shape cancer heterogeneity. We have used isobaric labeling to characterize the proteomic landscapes of 50 colorectal cancer cell lines and to decipher the functional consequences of soma...
Autores principales: | Roumeliotis, Theodoros I., Williams, Steven P., Gonçalves, Emanuel, Alsinet, Clara, Del Castillo Velasco-Herrera, Martin, Aben, Nanne, Ghavidel, Fatemeh Zamanzad, Michaut, Magali, Schubert, Michael, Price, Stacey, Wright, James C., Yu, Lu, Yang, Mi, Dienstmann, Rodrigo, Guinney, Justin, Beltrao, Pedro, Brazma, Alvis, Pardo, Mercedes, Stegle, Oliver, Adams, David J., Wessels, Lodewyk, Saez-Rodriguez, Julio, McDermott, Ultan, Choudhary, Jyoti S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583477/ https://www.ncbi.nlm.nih.gov/pubmed/28854368 http://dx.doi.org/10.1016/j.celrep.2017.08.010 |
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