Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans

DNA damage causally contributes to aging and age-related diseases. Mutations in nucleotide excision repair (NER) genes cause highly complex congenital syndromes characterized by growth retardation, cancer susceptibility, and accelerated aging in humans. Orthologous mutations in Caenorhabditis elegan...

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Detalles Bibliográficos
Autores principales: Edifizi, Diletta, Nolte, Hendrik, Babu, Vipin, Castells-Roca, Laia, Mueller, Michael M., Brodesser, Susanne, Krüger, Marcus, Schumacher, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583510/
https://www.ncbi.nlm.nih.gov/pubmed/28854356
http://dx.doi.org/10.1016/j.celrep.2017.08.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583510/
https://www.ncbi.nlm.nih.gov/pubmed/28854356
http://dx.doi.org/10.1016/j.celrep.2017.08.028

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