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Interleukin-19 is cardioprotective in dominant negative cyclic adenosine monophosphate response-element binding protein-mediated heart failure in a sex-specific manner

AIM: To investigate the role of interleukin-19 (IL-19) in a murine model of female-dominant heart failure (HF). METHODS: Expression of one copy of a phosphorylation-deficient cyclic adenosine monophosphate response-element binding protein (dnCREB) causes HF, with accelerated morbidity and mortality...

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Detalles Bibliográficos
Autores principales: Bruns, Danielle R, Ghincea, Alexander R, Ghincea, Christian V, Azuma, Yasu-Taka, Watson, Peter A, Autieri, Michael V, Walker, Lori A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583540/
https://www.ncbi.nlm.nih.gov/pubmed/28932356
http://dx.doi.org/10.4330/wjc.v9.i8.673