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Effects and mechanism of adenovirus-mediated phosphatase and tension homologue deleted on chromosome ten gene on collagen deposition in rat liver fibrosis

AIM: To evaluate the effects of phosphatase and tension homologue deleted on chromosome ten (PTEN) gene on collagen metabolism in hepatic fibrosis and the underlying mechanisms. METHODS: Rat primary hepatic stellate cells (HSCs) and human LX-2 cells were transfected with adenovirus containing cDNA c...

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Detalles Bibliográficos
Autores principales: Xie, Shu-Rui, An, Jun-Yan, Zheng, Li-Bo, Huo, Xiao-Xia, Guo, Jian, Shih, David, Zhang, Xiao-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583575/
https://www.ncbi.nlm.nih.gov/pubmed/28932082
http://dx.doi.org/10.3748/wjg.v23.i32.5904