Efficient method to create integration-free, virus-free, Myc and Lin28-free human induced pluripotent stem cells from adherent cells

AIM: Nonviral induced pluripotent stem cell (IPSC) reprogramming is not efficient without the oncogenes, Myc and Lin28. We describe a robust Myc and Lin28-free IPSC reprogramming approach using reprogramming molecules. METHODS: IPSC colony formation was compared in the presence and absence of Myc an...

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Detalles Bibliográficos
Autores principales: Kamath, Anant, Ternes, Sara, McGowan, Stephen, English, Anthony, Mallampalli, Rama, Moy, Alan B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583652/
https://www.ncbi.nlm.nih.gov/pubmed/28884008
http://dx.doi.org/10.4155/fsoa-2017-0028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583652/
https://www.ncbi.nlm.nih.gov/pubmed/28884008
http://dx.doi.org/10.4155/fsoa-2017-0028

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