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Efficient method to create integration-free, virus-free, Myc and Lin28-free human induced pluripotent stem cells from adherent cells

AIM: Nonviral induced pluripotent stem cell (IPSC) reprogramming is not efficient without the oncogenes, Myc and Lin28. We describe a robust Myc and Lin28-free IPSC reprogramming approach using reprogramming molecules. METHODS: IPSC colony formation was compared in the presence and absence of Myc an...

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Detalles Bibliográficos
Autores principales:	Kamath, Anant, Ternes, Sara, McGowan, Stephen, English, Anthony, Mallampalli, Rama, Moy, Alan B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Science Ltd 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583652/ https://www.ncbi.nlm.nih.gov/pubmed/28884008 http://dx.doi.org/10.4155/fsoa-2017-0028

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