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Identifying relationships between unrelated pharmaceutical target proteins on the basis of shared active compounds

AIM: Computational exploration of small-molecule-based relationships between target proteins from different families. MATERIALS & METHODS: Target annotations of drugs and other bioactive compounds were systematically analyzed on the basis of high-confidence activity data. RESULTS: A total of 286...

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Detalles Bibliográficos
Autores principales: Miljković, Filip, Kunimoto, Ryo, Bajorath, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583696/
https://www.ncbi.nlm.nih.gov/pubmed/28884009
http://dx.doi.org/10.4155/fsoa-2017-0037