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Protein clustering for cell polarity: Par-3 as a paradigm
The scaffold protein Par-3 ( Drosophila Bazooka) is a central organizer of cell polarity across animals. This review focuses on how the clustering of Par-3 contributes to cell polarity. It begins with the Par-3 homo-oligomerization mechanism and its regulation by Par-1 phosphorylation. The role of p...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000Research
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583741/ https://www.ncbi.nlm.nih.gov/pubmed/29026528 http://dx.doi.org/10.12688/f1000research.11976.1 |