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Accumulation of HIV-1 drug resistance in patients on a standard thymidine analogue-based first line antiretroviral therapy after virological failure: implications for the activity of next-line regimens from a longitudinal study in Mozambique

BACKGROUND: We describe the accumulation of HIV-1 drug resistance and its effect on the activity of next-line components in patients with virological failure (HIV-1 RNA >1000 copies/mL) after 1 year (t1) of first-line antiretroviral therapy (ART) not switching to second-line drugs for one additio...

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Detalles Bibliográficos
Autores principales: De Luca, Andrea, Sidumo, Zita Jorge, Zanelli, Giacomo, Magid, Noorjehan Abdul, Luhanga, Richard, Brambilla, Davide, Liotta, Giuseppe, Mancinelli, Sandro, Marazzi, Maria Cristina, Palombi, Leonardo, Ceffa, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584020/
https://www.ncbi.nlm.nih.gov/pubmed/28870148
http://dx.doi.org/10.1186/s12879-017-2709-x