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Accumulation of HIV-1 drug resistance in patients on a standard thymidine analogue-based first line antiretroviral therapy after virological failure: implications for the activity of next-line regimens from a longitudinal study in Mozambique
BACKGROUND: We describe the accumulation of HIV-1 drug resistance and its effect on the activity of next-line components in patients with virological failure (HIV-1 RNA >1000 copies/mL) after 1 year (t1) of first-line antiretroviral therapy (ART) not switching to second-line drugs for one additio...
Autores principales: | De Luca, Andrea, Sidumo, Zita Jorge, Zanelli, Giacomo, Magid, Noorjehan Abdul, Luhanga, Richard, Brambilla, Davide, Liotta, Giuseppe, Mancinelli, Sandro, Marazzi, Maria Cristina, Palombi, Leonardo, Ceffa, Susanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584020/ https://www.ncbi.nlm.nih.gov/pubmed/28870148 http://dx.doi.org/10.1186/s12879-017-2709-x |
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