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Chronic dialysis, NAT2 polymorphisms, and the risk of isoniazid-induced encephalopathy – case report and literature review

BACKGROUND: Isoniazid is the most widely used anti-tuberculosis agent, yet it may lead to life-threatening complications. CASE PRESENTATION: Here we report the case of a chronic hemodialysis patient who developed severe encephalopathy after the start of isoniazid. Blood levels of isoniazid were elev...

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Detalles Bibliográficos
Autores principales: Constantinescu, Stefan Matei, Buysschaert, Benoit, Haufroid, Vincent, Broly, Franck, Jadoul, Michel, Morelle, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584033/
https://www.ncbi.nlm.nih.gov/pubmed/28870161
http://dx.doi.org/10.1186/s12882-017-0703-6