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The N- and C-terminal carbohydrate recognition domains of Haemonchus contortus galectin bind to distinct receptors of goat PBMC and contribute differently to its immunomodulatory functions in host-parasite interactions

BACKGROUND: Hco-gal-m is a tandem-repeat galectin isolated from the adult worm of Haemonchus contortus. A growing body of studies have demonstrated that Hco-gal-m could exert its immunomodulatory effects on host peripheral blood mononuclear cells (PBMC) to facilitate the immune evasion. Our previous...

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Detalles Bibliográficos
Autores principales: Lu, MingMin, Tian, XiaoWei, Yang, XinChao, Yuan, Cheng, Ehsan, Muhammad, Liu, XinChao, Yan, RuoFeng, Xu, LiXin, Song, XiaoKai, Li, XiangRui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584048/
https://www.ncbi.nlm.nih.gov/pubmed/28870237
http://dx.doi.org/10.1186/s13071-017-2353-8