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Blimp-1–dependent and –independent natural antibody production by B-1 and B-1–derived plasma cells

Natural antibodies contribute to tissue homeostasis and protect against infections. They are secreted constitutively without external antigenic stimulation. The differentiation state and regulatory pathways that enable continuous natural antibody production by B-1 cells, the main cellular source in...

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Detalles Bibliográficos
Autores principales: Savage, Hannah P., Yenson, Vanessa M., Sawhney, Sanjam S., Mousseau, Betty J., Lund, Frances E., Baumgarth, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584113/
https://www.ncbi.nlm.nih.gov/pubmed/28698287
http://dx.doi.org/10.1084/jem.20161122