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Protein kinase D at the Golgi controls NLRP3 inflammasome activation

The inflammasomes are multiprotein complexes sensing tissue damage and infectious agents to initiate innate immune responses. Different inflammasomes containing distinct sensor molecules exist. The NLRP3 inflammasome is unique as it detects a variety of danger signals. It has been reported that NLRP...

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Detalles Bibliográficos
Autores principales: Zhang, Zhirong, Meszaros, Gergö, He, Wan-ting, Xu, Yanfang, de Fatima Magliarelli, Helena, Mailly, Laurent, Mihlan, Michael, Liu, Yansheng, Puig Gámez, Marta, Goginashvili, Alexander, Pasquier, Adrien, Bielska, Olga, Neven, Bénédicte, Quartier, Pierre, Aebersold, Rudolf, Baumert, Thomas F., Georgel, Philippe, Han, Jiahuai, Ricci, Romeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584123/
https://www.ncbi.nlm.nih.gov/pubmed/28716882
http://dx.doi.org/10.1084/jem.20162040