PPARs as determinants of the estrogen receptor lineage: use of synthetic lethality for the treatment of estrogen receptor-negative breast cancer

THE DILEMMA: Estrogen receptora-negative (ER-) breast cancer lacks a specific critical target to control tumor progression. THE OBJECTIVE: To identify mechanisms that enable increased expression of the ER+ lineage in an otherwise ER- breast cancer. PREFACE: The nuclear receptor superfamily members P...

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Detalles Bibliográficos
Autores principales: Glazer, Robert I., Kopelovich, Levy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584135/
https://www.ncbi.nlm.nih.gov/pubmed/28881566
http://dx.doi.org/10.18632/oncotarget.17302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584135/
https://www.ncbi.nlm.nih.gov/pubmed/28881566
http://dx.doi.org/10.18632/oncotarget.17302

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