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Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting

Acidic clusters act as sorting signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulation of MHC-I by HIV-1 Nef. To find acidic cluster sorting machinery, we performed a gene-trap screen and identified the medium subunit (µ1) of the clathrin adaptor AP-1 as...

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Detalles Bibliográficos
Autores principales: Navarro Negredo, Paloma, Edgar, James R., Wrobel, Antoni G., Zaccai, Nathan R., Antrobus, Robin, Owen, David J., Robinson, Margaret S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584140/
https://www.ncbi.nlm.nih.gov/pubmed/28743825
http://dx.doi.org/10.1083/jcb.201602058