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Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7

Chronic inflammation is a well-known risk factor in development of intestinal tumorigenesis, although the exact mechanisms underlying development of colitis-associated cancer (CAC) still remain obscure. The activity and function of immunoproteasome has been extensively analyzed in the context of inf...

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Detalles Bibliográficos
Autores principales: Vachharajani, Niyati, Joeris, Thorsten, Luu, Maik, Hartmann, Sabrina, Pautz, Sabine, Jenike, Elena, Pantazis, Georgios, Prinz, Immo, Hofer, Markus J., Steinhoff, Ulrich, Visekruna, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584149/
https://www.ncbi.nlm.nih.gov/pubmed/28881574
http://dx.doi.org/10.18632/oncotarget.14579