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A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas

Recent literature suggests that most widely used ovarian cancer (OVCA) cell models do not recapitulate the molecular features of clinical tumors. To address this limitation, we generated 18 cell lines and 3 corresponding patient-derived xenografts predominantly from high-grade serous carcinoma (HGSO...

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Detalles Bibliográficos
Autores principales: Thu, Kelsie L., Papari-Zareei, Mahboubeh, Stastny, Victor, Song, Kai, Peyton, Michael, Martinez, Victor D., Zhang, Yu-An, Castro, Isabel B., Varella-Garcia, Marileila, Liang, Hanquan, Xing, Chao, Kittler, Ralf, Milchgrub, Sara, Castrillon, Diego H., Davidson, Heather L., Reynolds, C Patrick, Lam, Wan L., Lea, Jayanthi, Gazdar, Adi F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584155/
https://www.ncbi.nlm.nih.gov/pubmed/28881577
http://dx.doi.org/10.18632/oncotarget.9929