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A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas
Recent literature suggests that most widely used ovarian cancer (OVCA) cell models do not recapitulate the molecular features of clinical tumors. To address this limitation, we generated 18 cell lines and 3 corresponding patient-derived xenografts predominantly from high-grade serous carcinoma (HGSO...
Autores principales: | Thu, Kelsie L., Papari-Zareei, Mahboubeh, Stastny, Victor, Song, Kai, Peyton, Michael, Martinez, Victor D., Zhang, Yu-An, Castro, Isabel B., Varella-Garcia, Marileila, Liang, Hanquan, Xing, Chao, Kittler, Ralf, Milchgrub, Sara, Castrillon, Diego H., Davidson, Heather L., Reynolds, C Patrick, Lam, Wan L., Lea, Jayanthi, Gazdar, Adi F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584155/ https://www.ncbi.nlm.nih.gov/pubmed/28881577 http://dx.doi.org/10.18632/oncotarget.9929 |
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