TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import

Most proteins destined for the peroxisomal matrix depend on the peroxisomal targeting signals (PTSs), which require the PTS receptor PEX5, whose deficiency causes fatal human peroxisomal biogenesis disorders (PBDs). TRIM37 gene mutations cause muscle–liver–brain–eye (mulibrey) nanism. We found that...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Xia, Zhi-Jie, Farré, Jean-Claude, Subramani, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584156/
https://www.ncbi.nlm.nih.gov/pubmed/28724525
http://dx.doi.org/10.1083/jcb.201611170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584156/
https://www.ncbi.nlm.nih.gov/pubmed/28724525
http://dx.doi.org/10.1083/jcb.201611170

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