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Methylation of HPV and a tumor suppressor gene reveals anal cancer and precursor lesions

We studied DNA methylation patterns of human papillomavirus (HPV) and tumor suppressor gene EPB41L3 in 148 anal and perianal biopsies to determine whether high levels of methylation would be associated with anal intraepithelial neoplasia (AIN). The most prevalent HPV type was HPV16, detected in 54%...

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Detalles Bibliográficos
Autores principales: Lorincz, Attila T., Nathan, Mayura, Reuter, Caroline, Warman, Rhian, Thaha, Mohamed A., Sheaff, Michael, Vasiljevic, Natasa, Ahmad, Amar, Cuzick, Jack, Sasieni, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584159/
https://www.ncbi.nlm.nih.gov/pubmed/28881579
http://dx.doi.org/10.18632/oncotarget.17984