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Methylation of HPV and a tumor suppressor gene reveals anal cancer and precursor lesions
We studied DNA methylation patterns of human papillomavirus (HPV) and tumor suppressor gene EPB41L3 in 148 anal and perianal biopsies to determine whether high levels of methylation would be associated with anal intraepithelial neoplasia (AIN). The most prevalent HPV type was HPV16, detected in 54%...
Autores principales: | Lorincz, Attila T., Nathan, Mayura, Reuter, Caroline, Warman, Rhian, Thaha, Mohamed A., Sheaff, Michael, Vasiljevic, Natasa, Ahmad, Amar, Cuzick, Jack, Sasieni, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584159/ https://www.ncbi.nlm.nih.gov/pubmed/28881579 http://dx.doi.org/10.18632/oncotarget.17984 |
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