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Dimerization of EGFR and HER2 induces breast cancer cell motility through STAT1-dependent ACTA2 induction

The dimerization of EGFR and HER2 is associated with poor prognosis such as induction of tumor growth and cell invasion compared to when EGFR remains as a homodimer. However, the mechanism for events after dimerization in breast cancer models is not clear. We found that expressions of alpha-smooth m...

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Detalles Bibliográficos
Autores principales: Jeon, Myeongjin, You, Daeun, Bae, Soo Youn, Kim, Seok Won, Nam, Seok Jin, Kim, Hyeon Ho, Kim, Sangmin, Lee, Jeong Eon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584169/
https://www.ncbi.nlm.nih.gov/pubmed/28881584
http://dx.doi.org/10.18632/oncotarget.10843