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C/EBP-δ positively regulates MDSC expansion and endothelial VEGFR2 expression in tumor development
Vascular endothelial cells and Gr-1+CD11b+ myeloid derived suppressor cells (MDSCs) are two important components that constitute the tumor microenvironment. Targeting these cells offers the potential to halt tumor growth. In this study, we report a common mediator in C/EBP-δ that regulates both comp...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584171/ https://www.ncbi.nlm.nih.gov/pubmed/28881585 http://dx.doi.org/10.18632/oncotarget.16410 |