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C/EBP-δ positively regulates MDSC expansion and endothelial VEGFR2 expression in tumor development

Vascular endothelial cells and Gr-1+CD11b+ myeloid derived suppressor cells (MDSCs) are two important components that constitute the tumor microenvironment. Targeting these cells offers the potential to halt tumor growth. In this study, we report a common mediator in C/EBP-δ that regulates both comp...

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Detalles Bibliográficos
Autores principales: Min, Yongfen, Li, Jingdong, Qu, Peng, Lin, P. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584171/
https://www.ncbi.nlm.nih.gov/pubmed/28881585
http://dx.doi.org/10.18632/oncotarget.16410