Cargando…
C/EBP-δ positively regulates MDSC expansion and endothelial VEGFR2 expression in tumor development
Vascular endothelial cells and Gr-1+CD11b+ myeloid derived suppressor cells (MDSCs) are two important components that constitute the tumor microenvironment. Targeting these cells offers the potential to halt tumor growth. In this study, we report a common mediator in C/EBP-δ that regulates both comp...
Autores principales: | Min, Yongfen, Li, Jingdong, Qu, Peng, Lin, P. Charles |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584171/ https://www.ncbi.nlm.nih.gov/pubmed/28881585 http://dx.doi.org/10.18632/oncotarget.16410 |
Ejemplares similares
-
C/EBP-δ regulates VEGF-C autocrine signaling in lymphangiogenesis and metastasis of lung cancer through HIF-1α
por: Min, Yongfen, et al.
Publicado: (2011) -
Dual negative roles of C/EBPα in the expansion and pro-tumor functions of MDSCs
por: Mackert, John R., et al.
Publicado: (2017) -
Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration
por: Kim, Sinae, et al.
Publicado: (2016) -
C/EBPδ Gene Targets in Human Keratinocytes
por: Borrelli, Serena, et al.
Publicado: (2010) -
Vav1 is Essential for HIF-1α Activation via a Lysosomal VEGFR1-Mediated Degradation Mechanism in Endothelial Cells
por: Hong, Jaewoo, et al.
Publicado: (2020)