Adenomatous polyposis coli nucleates actin assembly to drive cell migration and microtubule-induced focal adhesion turnover

Cell motility depends on tight coordination between the microtubule (MT) and actin cytoskeletons, but the mechanisms underlying this MT–actin cross talk have remained poorly understood. Here, we show that the tumor suppressor protein adenomatous polyposis coli (APC), which is a known MT-associated p...

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Detalles Bibliográficos
Autores principales: Juanes, M. Angeles, Bouguenina, Habib, Eskin, Julian A., Jaiswal, Richa, Badache, Ali, Goode, Bruce L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584174/
https://www.ncbi.nlm.nih.gov/pubmed/28663347
http://dx.doi.org/10.1083/jcb.201702007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584174/
https://www.ncbi.nlm.nih.gov/pubmed/28663347
http://dx.doi.org/10.1083/jcb.201702007

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