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Adenomatous polyposis coli nucleates actin assembly to drive cell migration and microtubule-induced focal adhesion turnover
Cell motility depends on tight coordination between the microtubule (MT) and actin cytoskeletons, but the mechanisms underlying this MT–actin cross talk have remained poorly understood. Here, we show that the tumor suppressor protein adenomatous polyposis coli (APC), which is a known MT-associated p...
Autores principales: | Juanes, M. Angeles, Bouguenina, Habib, Eskin, Julian A., Jaiswal, Richa, Badache, Ali, Goode, Bruce L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584174/ https://www.ncbi.nlm.nih.gov/pubmed/28663347 http://dx.doi.org/10.1083/jcb.201702007 |
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