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Reciprocal regulation of signaling and endocytosis: Implications for the evolving cancer cell

Cell surface receptor uptake via clathrin-mediated endocytosis (CME) and subsequent intracellular sorting for degradation or recycling regulates the strength and specificity of downstream signaling. Signaling, in turn, modulates early endocytic trafficking. This reciprocal regulation of signaling an...

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Detalles Bibliográficos
Autor principal: Schmid, Sandra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584184/
https://www.ncbi.nlm.nih.gov/pubmed/28674108
http://dx.doi.org/10.1083/jcb.201705017