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The miR-106a~363(Xpcl1) miRNA cluster induces murine T cell lymphoma despite transcriptional activation of the p27(Kip1) cell cycle inhibitor
The miR-106a~363 cluster encodes 6 miRNAs on the X-chromosome which are abundant in blood cells and overexpressed in a variety of malignancies. The constituent miRNA of miR-106a~363 have functional activities in vitro that are predicted to be both oncogenic and tumor suppressive, yet little is known...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584189/ https://www.ncbi.nlm.nih.gov/pubmed/28881594 http://dx.doi.org/10.18632/oncotarget.16932 |