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From DNA binding to transcriptional activation: Is the TALE complete?

How transcription factors (TFs) control enhancer and promoter functions to effect changes in gene expression is an important question. In this issue, Hau et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201701154) show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promote...

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Detalles Bibliográficos
Autor principal: Bobola, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584190/
https://www.ncbi.nlm.nih.gov/pubmed/28801318
http://dx.doi.org/10.1083/jcb.201706113