From DNA binding to transcriptional activation: Is the TALE complete?

How transcription factors (TFs) control enhancer and promoter functions to effect changes in gene expression is an important question. In this issue, Hau et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201701154) show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promote...

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Detalles Bibliográficos
Autor principal: Bobola, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584190/
https://www.ncbi.nlm.nih.gov/pubmed/28801318
http://dx.doi.org/10.1083/jcb.201706113
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author Bobola, Nicoletta
author_facet Bobola, Nicoletta
author_sort Bobola, Nicoletta
collection PubMed
description How transcription factors (TFs) control enhancer and promoter functions to effect changes in gene expression is an important question. In this issue, Hau et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201701154) show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promoters to decompact chromatin and activate transcription.
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spelling pubmed-55841902018-03-04 From DNA binding to transcriptional activation: Is the TALE complete? Bobola, Nicoletta J Cell Biol Commentary How transcription factors (TFs) control enhancer and promoter functions to effect changes in gene expression is an important question. In this issue, Hau et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201701154) show that the TALE TF MEIS recruits the histone modifier PARP1/ARTD1 at promoters to decompact chromatin and activate transcription. The Rockefeller University Press 2017-09-04 /pmc/articles/PMC5584190/ /pubmed/28801318 http://dx.doi.org/10.1083/jcb.201706113 Text en © 2017 Bobola http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Bobola, Nicoletta
From DNA binding to transcriptional activation: Is the TALE complete?
title From DNA binding to transcriptional activation: Is the TALE complete?
title_full From DNA binding to transcriptional activation: Is the TALE complete?
title_fullStr From DNA binding to transcriptional activation: Is the TALE complete?
title_full_unstemmed From DNA binding to transcriptional activation: Is the TALE complete?
title_short From DNA binding to transcriptional activation: Is the TALE complete?
title_sort from dna binding to transcriptional activation: is the tale complete?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584190/
https://www.ncbi.nlm.nih.gov/pubmed/28801318
http://dx.doi.org/10.1083/jcb.201706113
work_keys_str_mv AT bobolanicoletta fromdnabindingtotranscriptionalactivationisthetalecomplete

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